Principal Scientist

Job Purpose: We are seeking a highly motivated Principal Scientist, with strong in vivo skills, to join our bacterial In Vivo Team within the Infectious Disease (ID) Research group. Our ID team is part of Vaccines Research, one of the three therapeutic aligned Research teams here at GSK. The successful candidate will conduct in vivo experiments using animal models of bacterial infection and will be the in vivo representative and subject matter expert within a larger project team. This role involves designing and executing the in vivo strategy for the project, including performing studies independently, while working closely with cross-functional teams to advance our understanding of bacterial infections and develop novel therapeutic interventions.

Key Accountabilities / Responsibilities:

• In Vivo Study Design and Execution: Design and execute in vivo studies to evaluate the efficacy and pharmacokinetics of potential therapeutic candidates for bacterial infections. Develop study protocols, conduct experiments, coordinate with internal and external stakeholders, and ensure compliance with regulatory requirements and ethical standards.
• Animal Model Development: Develop and optimize animal models of bacterial infections to mimic human disease conditions. Select appropriate animal species, strains, and models to address specific research questions and therapeutic targets.
• Data Collection and Analysis: Perform data collection, analysis, and interpretation of in vivo study results. Utilize statistical methods and data visualization techniques to draw meaningful conclusions and contribute to the understanding of disease mechanisms and therapeutic interventions.
• Project Representation: Serve as the project representative, providing scientific and strategic leadership in the field of in vivo research for bacterial infections. Contribute to the broader matrix team's development of innovative research strategies and drive scientific excellence within the team.
• Collaboration and Cross-functional Support: Collaborate with cross-functional teams to support the discovery and development of novel therapies for bacterial infections. Provide scientific input and support to project teams, contribute to study design discussions, and participate in project meetings.
• Laboratory Management and Compliance: Maintain laboratory equipment, supplies, and animal facilities in accordance with regulatory guidelines and GSK's safety standards. Ensure compliance with animal welfare regulations, ethical guidelines, and in accordance with IACUC standards and GSK's policies on the care and ethical treatment of animals.
• Scientific Communication and Collaboration: Effectively communicate scientific findings, research progress, and strategic insights to team members, internal stakeholders, senior management, and external scientific communities.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• PhD with 1+ years' experience, MS in relevant scientific discipline (e.g., Microbiology, Immunology, Pharmacology) or related field with 5-7 years, or a BS in a relevant scientific discipline with 8-10 years or more experience in a research setting.
• Minimum of 5 years of experience in conducting in vivo studies in the pharmaceutical or biotechnology industry, preferably in the field of bacterial infections.
• Experience designing and executing in vivo studies, including experience with animal models, dosing, sample collection, and data analysis.
• Experience working with bacterial infections, including understanding of disease mechanisms, host-pathogen interactions, and therapeutic interventions.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Proven track record of scientific leadership, strategic thinking, and cross-functional collaboration.
• Strong analytical and problem-solving skills, with the ability to interpret complex data and draw meaningful conclusions.
• Excellent communication and presentation skills, with the ability to effectively convey scientific concepts to diverse audiences.
• Proven track record to lead and deliver solutions for implementing GSK processes to conduct in vivo research in a regulated, safe, and well-executed environment.

Why GSK?

Our values and expectations are at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

• Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
• Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
• Continuously looking for opportunities to learn, build skills and share learning.
• Sustaining energy and well-being
• Building strong relationships and collaboration, honest and open conversations.
• Budgeting and cost-consciousness

*This is a job description to aide in the job posting, but does not include all job evaluation details.

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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