2025 Summer Intern - Protein Engineering and AI Model Development

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people's varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

2025 Summer Intern - Data Science

We advance science so that we all have more time with the people we love.

Department Summary

Roche Diagnostics is a global leader in diagnostics, revolutionizing healthcare by combining cutting-edge technology with innovative research. Our Protein Engineering team is committed to advancing diagnostic solutions through the development of novel tools and methodologies. We aim to harness the power of artificial intelligence and protein language models to push the boundaries of protein engineering.

This internship position is located in Santa Clara, on-site.

The Opportunity

• Collaborate with the Protein Engineering team to develop computational tools for protein analysis and design.

• Explore and utilize protein language models (e.g., AlphaFold, ESMFold, ProtT5) to analyze and predict protein structure and function.

• Fine-tune existing protein language models for specific protein engineering applications.

• Perform data preprocessing, feature extraction, and model evaluation using large-scale protein datasets.

• Collaborate with wet lab experts to integrate computational insights with experimental validation and design strategies.

• Develop user-friendly scripts and workflows for automating protein engineering tasks.

• Document project progress, results, and methodologies, preparing a final presentation for the team.

Program Highlights

• Intensive 12-weeks, full-time (40 hours per week) paid internship.

• Program start dates are in May/June (Summer).

• A stipend, based on location, will be provided to help alleviate costs associated with the internship.

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

Who You Are (Required)

Required Education: You meet one of the following criteria:

• Must have attained a Bachelor's Degree (not currently enrolled in a graduate program).

• Must be pursuing a Master's Degree (enrolled student).

• Must have attained a Master's Degree.

• Must be pursuing a PhD (enrolled student).

Required Majors

• Bioinformatics, Computational Biology, Computer Science, Biotechnology, or a related field.

Required Skills

• Strong programming skills in Python and familiarity with relevant libraries (e.g., PyTorch, TensorFlow, scikit-learn).

• Basic understanding of protein structure and function, as well as protein engineering principles.

• Experience with machine learning techniques and/or computational biology tools. and fine tuning protein language models.

• Familiarity with protein language models and AI-based approaches in biological research is a plus.

• Excellent problem-solving skills and the ability to work independently and collaboratively.

Preferred Knowledge, Skills, and Qualifications

• Excellent communication, collaboration, and interpersonal skills.

• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is $45-$50 hour.Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

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At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

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