Senior Director of Commercial Manufacturing & Supply Chain Finance

Job Description

General Summary:

Vertex is growing at a rapid pace with challenging and exciting opportunities for motivated professionals who are keen to contribute to the Vertex mission to invest in scientific innovation to create transformative medicines for people with serious diseases. As we continue to grow and scale, we are seeking a skilled Senior Director of Finance to lead financial strategy and operations for our Commercial Manufacturing & Supply Chain (CMSC) function within our Biopharmaceutical Sciences and Manufacturing Operations (BSMO) organization.

As a key leader in our Finance function, the Senior Director of CMSC Finance will play a critical role in shaping financial strategy, supporting strategic decision-making and driving cost efficiencies for Vertex's commercial manufacturing and supply chain operations. This individual will work closely with senior leadership and cross-functional teams to optimize performance, mitigate risks, and enhance financial processes in a fast-moving, innovation-driven environment.

Key Responsibilities:

• Lead a team of Finance Business Partners, ensuring alignment across functions while identifying opportunities to invest strategically, optimize costs and mitigate risks, including supporting long term portfolio prioritization decision making.
• Partner with senior leadership in Commercial Manufacturing & Supply Chain to develop and execute financial strategies aligned with business objectives.
• Oversee financial planning and analysis (FP&A) processes, including budgeting, forecasting, variance analysis, scenario modeling and long-term planning for CMSC, providing insightful and influential forward-looking direction to ensure data-driven decision-making.
• Provide executive-level insights for key business decisions, including cost optimization, capital investments, and financial risk management.
• Collaborate closely with the Senior Director of Cost Accounting and Inventory Finance to develop and track key performance indicators (KPIs) that drive operational efficiencies.
• Support supplier negotiations and production planning by collaborating with External Manufacturing and Strategic Sourcing teams.
• Partner with Supply Chain leaders to drive excellence and best practices in the Sales & Operations Planning (S&OP) process, ensuring seamless alignment between demand forecasts, supply chain capabilities, and financial targets to optimize decision-making and resource allocation.
• Lead monthly, quarterly, and annual financial close processes for manufacturing and supply chain finance.
• Ensure accurate financial reporting and compliance with internal controls, accounting policies (GAAP/IFRS), and regulatory requirements.
• Drive continuous process improvement, leveraging automation, technology, and financial best practices to support the company's expansion into new therapeutic areas and global markets.
• Builds and manages a high-performing CMSC Finance team that meets increasing needs and requirements across the business and helps drive the overall organization forward.
• Develops and coaches team members to encourage growth and new opportunities and creates an atmosphere of inclusivity across the team.

Key Knowledge, Skills and Competencies:

• Models Vertex's Values, Behaviors and Norms. Critically this role requires an expert ability to influence without authority at the highest level and collaborate effectively in support of shared goals.
• Exceptional interpersonal, written, and verbal communication skills.
• Experience in leading manufacturing and technical operations finance teams ideally for businesses with both external contract manufacturing networks and internal manufacturing facilities
• Ability to lead and drive change in an evolving business environment, coordinating processes involving large numbers of people, complex systems, and tight deadlines to deliver innovative solutions.
• Strong understanding of pharmaceutical sciences, manufacturing, and supply chain operations, enabling quick and effective decision-making.
• Expertise in financial modeling, ERP systems (Oracle preferred), cost accounting and supply chain analytics.
• Proven experience managing finance teams, driving financial performance and influencing executive decision-making.

Education and Experience:

• Bachelor's degree in business, Finance or Accounting.
• MBA and CPA a plus.
• Typically requires 15 years of relevant experience in a finance managerial role demonstrating strong technical and analytical skills and a track record of success working in a team-based environment or the equivalent combination of education and experience.
• Global pharmaceutical/biotechnology industry experience required.

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Flex Designation:

Flex Eligibility Status:

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com