Business Systems Senior Analyst

Job Description

General Summary:

This role will independently build and apply expertise of the POMSnet Aquila Manufacturing Execution System (MES) to support Manufacturing Operations and Supply Chain current and emerging priorities. This role requires working cross functionally to convert business requirements into system requirements then leading the associated implementation activities while ensuring compliance with applicable Quality requirements. Management skills are needed to ensure activities are completed on time and within budget. As a trusted partner, this individual is expected to handle issues when escalated, and champion system improvements to improve operational and supply chain functions.

Key Duties and Responsibilities:

• Manage system master data for rooms, equipment, recipes, worksheets, items, material flows, and other elements as required.
• Author minor configuration changes to MES worksheets and recipes
• Provide training and resolution to system issues when an escalation path is needed.
• Understand Vertex goals and apply them to improve the MES system in a targeted manner.
• Work cross functionally with the Vertex Quality organizations and DTE to ensure implementations, change controls, change actions, documentation revisions and similar are completed in a compliant manner.
• Demonstrate how MES and integrated digital systems improve quality, reduce defects and improve efficiency. Translate this into KPI's and dashboards for stakeholder review.
• Envision what the MES user interface will consist of and work with stakeholders and a recipe author to optimize the system
• Manage the change request backlog
• Develop and execute to a schedule, communicate to key stakeholders at appropriate frequency, and escalate when required.
• Complete all training and assigned tasks on-time while delivering effective solutions.

Knowledge and Skills:

• Proficient user of POMSnet Aquilla MES or equivalent MES system.
• Knowledgeable in object-based programming and Phase Transition Logic concepts.
• Understanding design methodologies for recipes and worksheets used in Cell and Gene Therapy Manufacturing.
• Proficient understanding of recipe authoring concepts used in object based and phase transition logic programming.
• Proficient in GMP principles and the Quality Management systems.
• Proficient understanding of the digital system landscapes as deployed in the Biopharmaceutical industry.
• Work cross functionally to prioritize tasks and align with business needs by gathering end user data and converting them into system requirements.
• Proven ability to successfully operate in a dynamic, high impact, and highly visible role.

Education and Experience:

• Typically requires 3 years of experience working with POMSnet Aquilla MES or similar system.
• BS in a Science, Engineering, or equivalent related field.
• Experience working in a GMP Manufacturing or another regulated environment.
• Proficient in Microsoft Office

#LI-onsite

Flex Designation:

Flex Eligibility Status:

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com