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SYFOVRE Strategy Lead

Apellis Pharmaceuticals, Inc.
life insurance, flex time, 401(k)
United States, Massachusetts, Waltham
100 5th Avenue (Show on map)
May 05, 2025

Position Summary:

The SYFOVRE Strategy Lead is accountable for leading a cross-functional team (Development, Medical, Medical Advisor, Commercial, Technical Operations, and Corporate Strategy) to develop and to drive cross-functional alignment of integrated strategies from ideation through life-cycle management. This role has broad impact on development, regulatory, and commercialization strategy, reporting to the Chief Business Officer.

This individual will provide leadership across drug development activities from POC through commercialization, ensuring the achievement of both program and Apellis goals. The ideal candidate will be a strategic and entrepreneurial leader that is well-versed in drug development and commercialization. This individual will be a strong influencer who can integrate multiple perspectives effectively, align stakeholders across functions and organization levels, problem solve and achieve the program goals.

Key Responsibilities Include:



  • Serve as the single point of accountability for overall asset strategy, leading a cross-functional team (Development, Medical, Medical Advisor, Commercial, Technical Operations & Corporate Strategy) from ideation through life-cycle management.
  • Own and drive strategic direction through the Strategy Team, including development of Integrated Asset Strategy, Indication Selection, and Target Product Profiles, and to drive cross-functional alignment of development strategy, regulatory strategy, launch sequencing, 3M strategy, and lifecycle strategy management.
  • Serve as the conduit to the Executive Committee for program strategies and performance against strategic initiatives.
  • Drive governance to ensure functional teams develop recommendations, and Strategy Teams evaluates these against strategic objectives. Manage issue resolution with a clear escalation path to the Executive Committee.
  • Provide matrix leadership for cross-functional team ensuring budget and resourcing is allocated for achievement of project scope, timelines, and objectives to maximize the value of the asset.
  • Ensure alignment between Pipeline Team management of the research portfolio and corporate strategy through proof of concept, as appropriate.
  • Serve as a core member of the Portfolio Prioritization Committee (PPC) responsible for strategy and portfolio prioritization at the corporate level.
  • Foster a culture of collaboration where functional experts participate in working teams aligned to deliverables with shared accountability for outcomes.
  • Establish and maintain regular cross-functional touchpoints focused on execution alignment.
  • Serve as an internal and external ambassador for the asset and its therapeutic area, fostering broad engagement to cultivate strategic relationships and enabling overall integration of external insights to inform program strategies


Education, Registration & Certification:



  • MBA or equivalent business experience
  • Advanced degrees in Life Sciences (PhD, MD, M.Sc., Pharm.D., or equivalent) preferred


Experience:



  • 10-15 years of biopharmaceutical experience in R&D and Commercialized products
  • Proven track record as a cross-functional leader in matrixed environments
  • Demonstrated success in program/portfolio management
  • Strong understanding of drug development process from POC through approval and launch
  • Experience with strategic planning and lifecycle management


Skills, Knowledge & Abilities:



  • Exceptional leadership and influence skills in matrix environments
  • Strong strategic thinking and facilitation of efficient decision-making
  • Excellence in stakeholder management and communication
  • Proven ability to drive alignment across functions
  • Track record of delivering results against key milestones
  • Ability to synthesize complex information into clear strategic direction



Benefits and Perks:

Apellis offers a comprehensive benefits package, including a 401(k) plan with company match, inclusive family building benefits, flexible time off, summer and winter shutdowns, paid family leave, disability and life insurance, and more! Visithttps://apellis.com/careers/ to learn more.

Company Background:

Apellis Pharmaceuticals, Inc. is a global biopharmaceutical company that combines courageous science and compassion to develop life-changing therapies for some of the most challenging diseases patients face. We ushered in the first new class of complement medicine in 15 years and now have two approved medicines targeting C3. These include the first and only therapy for geographic atrophy, a leading cause of blindness around the world. With nearly a dozen clinical and pre-clinical programs underway, we believe we have only begun to unlock the potential of targeting C3 across many serious diseases.

For more information, please visithttp://apellis.comor follow us onTwitterandLinkedIn

EEO Statement:

Apellis is an equal opportunity employer and complies with all applicable federal, state and local fair employment practices laws. Apellis strictly prohibits and does not tolerate discrimination against employees, applicants or any other covered persons because of race, color, religion, creed, national origin or ancestry, ethnicity, sex (including pregnancy), gender (including gender nonconformity and status as a transgender or transsexual individual), age, physical or mental disability, citizenship, past, current or prospective service in the uniformed services, genetic information, marital status, AIDS/HIV status, smoker/nonsmoker, and occupational pneumoconiosis or any other characteristic protected under applicable federal, state or local law.

For San Francisco postings: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

Other Duties:

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.



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