Intern - Downstream Process Development

Do you want to join a team where the mission is meaningful, the challenges are complex, and you can directly see the results of your hard work? Lundbeck Seattle BioPharmaceuticals (Lu-SBP), located in Bothell, Washington, is the Process Development Center of Excellence for Biologics within the global Lundbeck CMC organization. Since integrating into Lundbeck in October 2019, Lu-SBP has supported commercial launch of Lundbeck's first biologic product (Vyepti) and advancement of a growing biologics pipeline in collaboration with our Copenhagen-based Process Science & Validation Team. The Lu-SBP team leads and supports the development of new product candidates from cell line development through commercial validation of Drug Substance and Drug Product manufacturing processes. Join us on our journey to advance brain health and transform lives.

Internship will run approximately through mid-September - prefer local candidates attending local universities in the greater Seattle, WA area

POSITION SUMMARY
The Downstream Process Development Student Intern will support a team of scientists in developing production processes for therapeutic biologics in preclinical and clinical stages. The intern's primary focus will be learning to operate AKTA purification systems and Unicorn software, and conducting a Protein A resin cycling study to evaluate resin longevity and the effects of cleaning additives on resin performance (e.g., binding capacity, pressure, and visual characteristics).
Additional responsibilities may include assisting with general laboratory operations and completing a designated set of training documents. This role is highly collaborative, involving close interaction with teams in upstream processing, bioanalytics, analytical development, and formulation development.

ESSENTIAL FUNCTIONS:
* Assist with chromatography, harvest, and formulation (UF/DF) operations
* Support downstream group with equipment maintenance, buffer preparation, inventory organization
* Assist in design and execution of purification screening, scouting and characterization experiments
* Support team in purification of biologic protein lots from micro-scale to pilot-scale to support upstream and downstream studies
* Present information and actively participate in discussions on laboratory practices, experimental execution and results
* Communicate and collaborate with team members and other functional areas
* Perform downstream laboratory tasks as described above following operating procedures and general laboratory safety guidelines. Biohazardous and hazardous materials are used in the laboratory
* Correctly document work performed, analyze and communicate results
* Assists with organization of laboratory and inventories
* Procure equipment and maintain Lab supplies

REQUIRED EDUCATION, EXPERIENCE AND SKILLS:
* Enrolled towards a BS or equivalent degree in the sciences.
* Completed introductory Biology and/or Chemistry coursework
* Some laboratory experience or basic understanding of laboratory principles and techniques
* Strong communication and collaboration skills
* Attention to detail
* Enthusiastic attitude and willingness to learn

PREFERRED EDUCATION, EXPERIENCE AND SKILLS:
* Practical experience in a laboratory environment
* Experience purifying proteins using column chromatography
* Practical chemistry knowledge including buffer chemistry
* Familiarity with principles of chromatography
* Familiarity with JMP statistical software

TRAVEL:
* Willingness/Ability to travel up to 2% domestically.

Notes: This work will directly support PACAP and VIP/PACAP

The range displayed is specifically for those potential hires who will work or reside in the state of Washington, if selected for this role, and may vary based on various factors such as the candidate's qualifications, skills, competencies and proficiency for the role. Salary Pay Range: $23/hour. This position is not eligible to participate in the company's benefits except those benefits that are required by law. #LI-LM1

Why Lundbeck

Lundbeck offers a robust and comprehensive benefits package to help employees live well and protect their health, family, and everyday life. Information regarding our benefit offering can be found on the U.S. career site.

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