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Principal GPU Software Engineer II

Roche Holdings Inc.
$162,600-302,000
United States, California, Santa Clara
2801 Scott Boulevard (Show on map)
Jul 02, 2025

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Roche Sequencing is developing ground-breaking next-generation sequencing products that allow scientists/clinicians powerful new avenues to investigate DNA, the blueprint of any lifeforms, in days, giving them the ability to understand health conditions such as cancer, HIV, COVID19 and more! We are not only changing science but changing lives through the development of frontier technologies that accelerate personalized healthcare.

We are looking for a Principal GPU Software Engineer to develop GPU-accelerated software targeted for real-time primary analysis on a DNA sequencing instrument.

The Opportunity:

  • Work closely with research and algorithm experts, accelerating bioinformatics techniques using GPU hardware

  • Proficient in developing GPU-accelerated software in C/C++, with familiarity in Python for signal processing numerical analytics

  • Support software development lifecycle and Design Control process, working closely with team members to continuously improve quality and feature sets of the software products, based on technical design and requirements specifications

  • Produce well documented software along with test and validation to build high quality output

  • Establish best practices for software development methodologies and standards to ensure the highest quality of the software product delivered to users

  • Proactively work with engineering and research teams to ensure all technical aspects of software development are accurately communicated to all stakeholders

Who You Are

  • You have a Bachelor's degree in Computer Science, Computer Engineering or related field plus 10 years of direct related experience; Master/PhD is a plus. Or, a combination of education and experience to perform at this level.

  • You have experience with Object-oriented programming in C++ and experience with GPU-accelerated C/C++ libraries such as CUDA, Thrust, etc.

  • You have experience with recent C++ compiler standards (C++14/17) as well as algorithm frameworks (boost, thrust, TBB, etc.).

  • You have experience in writing, debugging and optimizing parallel (CPU and GPU) Linux applications.

  • You have experience in utilizing popular ML frameworks such as TensorFlow or PyTorch to develop and deploy machine learning models for predictive analytics and classification tasks.

  • You have proven technical leadership skills to implement and integrate new technologies along with best practices.

Preferred Qualifications:

  • You have working knowledge of QSR/cGMP, ISO and Design Controls

  • You have experience with Python and digital signal processing

The expected salary range for this position based on the primary location of Santa Clara, CA is $162,600-302,000 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are not available for this position.

Who we are

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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