New 
Senior Applied Scientist
 Microsoft | |
 United States, Washington, Redmond | |
 Oct 16, 2025 | |
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OverviewThe Business & Industry Copilots group is a rapidly growing organization that is responsible for the Microsoft Dynamics 365 suite of products, Power Apps, Power Automate, Dataverse, AI Builder, Microsoft Industry Solution and more. Microsoft is considered one of the leaders in Software as a Service in the world of business applications and this organization is at the heart of how business applications are designed and delivered. We are looking for a Senior Applied Scientist to join our team! The Business and Industry Solutions (BIS) team is looking for a Senior Applied Scientist to drive innovation at the intersection of AI, experimentation, and enterprise systems. In this role, you will design and evaluate autonomous agents that deliver measurable improvements in accuracy, latency, and cost-efficiency. You'll lead rapid experimentation cycles, develop robust evaluation frameworks, and apply advanced techniques like reinforcement learning to enable multi-step reasoning and decision-making. You will collaborate across engineering, product, and partner teams to ensure agents are performant, secure, reliable, and extensible-empowering customers and partners to build on our platform. This is your opportunity to influence the next generation of AI-native business applications and deliver real-world impact at scale. This role would be ideal for an individual who has prior expertise in natural language processing (NLP), with a strong foundation in large language model (LLM) development, evaluation, and fine-tuning. They should have hands-on experience in applying advanced fine-tuning techniques-including instruction tuning, reinforcement learning from human feedback (RLHF), and tool-augmented generation-to build agents capable of multi-step reasoning and decision-making. Familiarity with prompt/context engineering, context-aware orchestration, and integrating LLMs with external tools and APIs is essential. Microsoft's mission is to empower every person and every organization on the planet to achieve more. As employees we come together with a growth mindset, innovate to empower others, and collaborate to realize our shared goals. Each day we build on our values of respect, integrity, and accountability to create a culture of inclusion where everyone can thrive at work and beyond.
ResponsibilitiesDeliver impactful solutions by executing highleverage data science and analytics initiatives within a product area or feature team, ensuring measurable improvements to user and business outcomes. Lead the design and implementation of advanced model finetuning pipelines, including Reinforcement Learning from Human Feedback (RLHF), to align AI system behavior with user intent and improve performance in realworld scenarios. Own complex, endtoend projects that combine technical depth with crossfunctional collaboration, influencing feature direction and prioritization rather than broad organizational investment decisions. Develop and maintain robust measurement systems, experimentation frameworks, and causal inference methodologies tailored to dynamic AI systems and enterprisescale environments. Leverage AI to streamline workflows and enhance team productivity through intelligent automation and innovation. | |