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BIOINFORMATICS PROGR 3 RP
Job Summary The Cardiovascular Genetics Center at University of California, San Francisco is seeking an experienced bioinfomatician to faciliate several lines of research that relate broadly to inherited forms of cardiovascular disease, regulation of gene expression in health and disease, and personalized genetic medicine. The incumbent will work closely with prinicpal investigators within the Genetic Center to design and implement analysis pipelines in several broad areas of computational biology including analysis of experimentally generated datasets in basic research, and analysis of patient-derived genomic data from UCSF patients as well as publicly available data repositories. The goal will be to make fundamental biological discoveries that can ultimately be translated to understanding, prevent, and treat heritable cardiovascular diseases.
More specifically, the role involves developing and utilizing computational tools and systems to analyze and interpret biological or other research data. Utilizes and develops algorithms, computational techniques, and statistical methodologies. Helps in the design of new experiments. Implements end-user needs in database searching and integration. Maintains the computational infrastructure and tracks the flow of samples and information for large-scale studies. Provides web-based bioinformatics and access to public and proprietary databases.
The scope of work will include anayzing biological datasets generated experimentally including but not limited to bulk and single cell multiomics sequencing, epigenomics data including ChIP-Seq and CUT&RUN, and imaging data including spatial transcriptomics; overlapping experimental data with publicaly available genomic and expression datasets including UK Biobank, All of Us, Heart Cell Atlas, and similar datasets. There will also be analysis of genome sequencing data including whole exome- and whole genome sequencing to discern rare and common variants implicated in cardiovascular disease.The incumbent will also implement machine learning algorithms to analyze biological datasets. There will be frequent collaboration with bench scientists and clinicians in a highly collegial and stimulating scientific environment.
The final salary and offer components are subject to additional approvals based on UC policy. Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement. The salary range for this position is $101,300 - $216,700(Annual Rate). To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html Department Description The Division of Cardiology is one of the largest clinical, research and training divisions of the Department of Medicine (DOM) at UCSF. Within the Division are sub-specialty sections for: Adult Congenital Heart Disease; Advanced Heart Failure, Transplant, and Pulmonary Hypertension; Cardiac Electrophysiology; Echocardiography and Cardiac Imaging; General Cardiology, Interventional Cardiology; and Prevention.
The Division runs several clinical practices in multiple sites, conducts basic and clinical research, and educates medical students, residents, clinical fellows and postdoctoral scholars through ACGME as well as non-ACGME training programs. In addition, the Division has significant and complex financial and administrative relationships with the Department of Medicine (DOM) and the UCSF Medical Center, as well as large patient care programs in the sections noted above, large clinical, Federal, and privately supported research programs and six faculty laboratories.
The Division has 74 full-time faculty, 13 non-faculty academics, 38 clinical fellows, 8 post-doctoral research fellows, and over 65 research support and administrative staff, and 12 staff centrally for fellowship support, non-sponsored finance, HR, digital communications, and faculty administrative support. The Division currently expends over $22 million per year in pursuit of its clinical, research, training, and service missions. While the Division is primarily split between the Parnassus and Mission Bay campuses, fellows have rotations at the Zuckerberg San Francisco General Hospital and the San Francisco Veterans Affairs Medical Center.
The Cardiovascular Genetics Center is housed within the Smith Cardiovascular Research Building at UCSF, a state-of-the-art facility housing dozens of basic and translational research groups, including several labs focused on computational biology, machine learning, or genetics. The incumbent will be part of this broad research community. Required Qualifications
- Bachelor's degree in biological science, computational / programming, or related area and / or equivalent experience / training
- A minimum of 3 years of relevant work experience in bioinformatics or computational biology
- Thorough knowledge of bioinformatics programming design, modification and implementation in relevant languages such as Python, R, and/or equivalent
- Understanding of relational databases, web interfaces, and operating systems
- Strong project management skills
- Thorough knowledge of modern biology and applicable field of research
- Communication skills to work with both technical and non-technical personnel in multiple fields of expertise and at various levels in the organization
- Ability to communicate technical information in a clear and concise manner
- Ability to interface with management on a regular basis
- Self motivated, work independently or as part of a team, able to learn quickly, meet deadlines and demonstrate problem solving skills
- Thorough knowledge of web, application and data security concepts and methods
- Familiarity with cloud-based computing and high-performance computing environments
- Proven expertise, as reflected in publication record, in analyzing high-throughput sequencing datasets, including RNA-sequencing, ATAC-sequencing, and chromatin occupancy studies
- Thorough In-depth knowledge of genomic databases, tools, and statistical frameworks
Preferred Qualifications
- PhD in Bioinformatics or a closely related field
About UCSF The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells. Pride Values UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.
In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu
Join us to find a rewarding career contributing to improving healthcare worldwide. Equal Employment Opportunity The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law. Job Code and Payroll Title 005227 BIOINFORMATICS PROGR 3 RP Job Category Research and Scientific Bargaining Unit Research and Public Service Professionals (RP) Location San Francisco, CA Additional Shift Details M-F 9-5PM |
University of California - San Francisco
Mar 05, 2026